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The drug name is Contrave. Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you need to err assisting caution and permit the FDA do its job and demand some investigation be done in order that the public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers found out that participants using this drug for a year, dropped a few pounds within one month and have kept the body weight off during the entire 56 weeks from the study. Contrave can be a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of many active ingredient, that might make them more efficient and safer. Combo-pilling is the newest fad or in addition to this the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that since right now there are no long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure level and pulse rate, and shouldn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients for the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if the tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone is used correctly, the naloxone is destroyed in the liver after that uptake in the intestines and contains no therapeutic effect. Buprenorphine could be the active substance; it really is absorbed underneath the tongue (and during the entire mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation if the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who may have had gastric bypass, in which the first area of the intestine is bypassed and the stomach contents empty into a more distal area of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the task with normal anatomy the place that the drug is taken up by the duodenum and transferred straight away to the liver from the portal vein, where it can be quickly and completely destroyed. After gastric bypass naloxone can be taken on by portions of the intestine that are not served from the portal system, causing blood amounts of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.