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Contrave is often a combination from the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which can be made up of several active ingredient, that might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that by right now there are no long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in those with seizure disorders. 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